A web of imprinting in stem cells
- PMID: 21885011
- DOI: 10.1016/j.stem.2011.08.008
A web of imprinting in stem cells
Abstract
Imprinted genes are the prototypical epigenetically regulated genes. On the basis of findings in adult lung stem cells, Zacharek et al. (2011) suggest in this issue of Cell Stem Cell that epigenetic silencing of imprinted genes is a common requirement for maintaining self-renewal in adult stem cell populations.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci.Cell Stem Cell. 2011 Sep 2;9(3):272-81. doi: 10.1016/j.stem.2011.07.007. Cell Stem Cell. 2011. PMID: 21885022 Free PMC article.
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