Converting human skin cells to neurons: a new tool to study and treat brain disorders?
- PMID: 21885012
- DOI: 10.1016/j.stem.2011.08.004
Converting human skin cells to neurons: a new tool to study and treat brain disorders?
Abstract
Recent publications in Cell Stem Cell (Son et al., 2011; Ambasudhan et al., 2011), PNAS (Pfisterer et al., 2011), and Nature (Caiazzo et al., 2011; Pang et al., 2011; Yoo et al., 2011) report that functional neurons can be directly generated from human fibroblast cells without going through the pluripotent state.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions.Cell Stem Cell. 2011 Aug 5;9(2):113-8. doi: 10.1016/j.stem.2011.07.002. Epub 2011 Jul 28. Cell Stem Cell. 2011. PMID: 21802386 Free PMC article.
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Conversion of mouse and human fibroblasts into functional spinal motor neurons.Cell Stem Cell. 2011 Sep 2;9(3):205-18. doi: 10.1016/j.stem.2011.07.014. Cell Stem Cell. 2011. PMID: 21852222 Free PMC article.
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