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Comment
. 2011 Sep 13;108(37):15013-4.
doi: 10.1073/pnas.1112014108. Epub 2011 Sep 1.

"Eppur si muove" (Yet it moves)

Vicent Moliner  1
Affiliations
Comment

"Eppur si muove" (Yet it moves)

Vicent Moliner. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Schematic representation of the origin of enzyme catalysis by the preorganized protein–substrate electrostatic interactions hypothesis and the controversial proposal of the protein promoting vibrations. Water molecules adapt to the charge distribution of the solute in the reactant (R) or the transition state (TS), as a reaction field, while vibrations would be randomly distributed. Electrostatic dipoles and promoting vibrations of the protein would be preoriented to stabilize the TS.
See this image and copyright information in PMC

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References

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