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Review
. 2011 Nov;23(6):574-8.
doi: 10.1097/BOR.0b013e32834b53cc.

Inclusion body myositis

Steven A Greenberg  1
Affiliations
Review

Inclusion body myositis

Steven A Greenberg. Curr Opin Rheumatol. 2011 Nov.

Abstract

Purpose of review: Sporadic inclusion body myositis (sIBM) is a poorly understood immune and degenerative disease of skeletal muscle. Here, current opinion of the nature of this disease is summarized.

Recent findings: Recent findings for sIBM include further characterization of muscle involvement through magnetic resonance imaging, the role of muscle as a host for immune cells, progress in the role of extranuclear TDP-43 in causing cellular injury, and the discovery of a new sIBM autoantibody.

Summary: sIBM understanding continues to advance, with progress regarding the mechanism of this disease.

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