Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Sep;26(3):99-100.
doi: 10.1007/s12288-010-0032-4. Epub 2010 Nov 2.

Acute psychosis: a presentation of cyanocobalamin deficiency megaloblastic anemia

Affiliations
Case Reports

Acute psychosis: a presentation of cyanocobalamin deficiency megaloblastic anemia

A K Tripathi et al. Indian J Hematol Blood Transfus. 2010 Sep.

Abstract

Cyanocobalamin deficiency is not rare in India. Patients present with megaloblastic anemia, pancytopenia and sometimes neuropsychiatric manifestations. Subacute combined degeneration of the cord, peripheral neuropathy, dementia, psychotic depression and paranoid schizophrenia are well reported. We are reporting a case of cyanocobalamine deficiency anemia who presented with acute psychosis which readily reversed on cyanocobalamin replacement.

Keywords: Cynocobalamine deficiency; Megaliblastic anemia; Psychosis; SACD; Vitamin B12.

PubMed Disclaimer

References

    1. Beck WS. Neuropsychiatric consequences of cobalamine deficiency. Adv Intern Med. 1991;36:33. - PubMed
    1. Victor M, Lear A. Subacute combined degeneration of the spinal cord: current concepts of the disease: value of serum B12 determinations in clarifying some of the common clinical problems. Am J Med. 1956;20:896. doi: 10.1016/0002-9343(56)90210-8. - DOI - PubMed
    1. Fraser TN. Cerebral manifestations of Addisonian pernicious anemia. Lancet. 1960;2:258. - PubMed
    1. Kumar S. Vit. B12 deficiency presenting with an acute reversible extrapyramidal syndrome. Neurol India. 2004;52(4):507–509. - PubMed
    1. Hector M, Burton JR (1998) What are the psychiatric manifestations of vit. B12 deficiency? J Am Geriatr Soc 36(12):405–412 - PubMed

Publication types

LinkOut - more resources