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. 2010 Sep;23(3):176-81.
doi: 10.1055/s-0030-1262985.

Enterocutaneous fistula associated with malignancy and prior radiation therapy

Luiz Felipe de Campos-Lobato  1 , Jon D Vogel
Affiliations

Enterocutaneous fistula associated with malignancy and prior radiation therapy

Luiz Felipe de Campos-Lobato et al. Clin Colon Rectal Surg. 2010 Sep.

Abstract

Enterocutaneous fistula (ECF) associated with cancer or radiation injury increases the complexity of normal management. Factors such as timing of additional adjuvant therapy or palliative care, technical considerations for operating on irradiated bowel, poor wound healing, increased risk of additional ECF, and decreased likelihood of spontaneous ECF closure all need to be considered in this scenario. Here the authors focus specifically on the management of ECF associated with cancer and/or radiation-induced injury to the bowel.

Keywords: Enterocutaneous fistula; cancer; management; radiation injury.

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References

    1. Edmunds L H, Jr, Williams G M, Welch C E. External fistulas arising from the gastro-intestinal tract. Ann Surg. 1960;152:445–471. - PMC - PubMed
    1. Joyce M R, Dietz D W. Management of complex gastrointestinal fistula. Curr Probl Surg. 2009;46(5):384–430. - PubMed
    1. Chamberlain R S, Kaufman H L, Danforth D N. Enterocutaneous fistula in cancer patients: etiology, management, outcome, and impact on further treatment. Am Surg. 1998;64(12):1204–1211. - PubMed
    1. Paris F, Fuks Z, Kang A, et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science. 2001;293(5528):293–297. - PubMed
    1. Zimmerer T, Böcker U, Wenz F, Singer M V. Medical prevention and treatment of acute and chronic radiation induced enteritis—is there any proven therapy? A short review. Z Gastroenterol. 2008;46(5):441–448. - PubMed