Prevalence of osteoporosis and osteopenia in advanced chronic obstructive pulmonary disease patients
- PMID: 21886952
- PMCID: PMC3162755
- DOI: 10.4103/0970-2113.83974
Prevalence of osteoporosis and osteopenia in advanced chronic obstructive pulmonary disease patients
Abstract
Background: Reduction of bone mineral density (BMD) is a known and established phenomenon in chronic obstructive pulmonary disease (COPD). However, there have been no data regarding osteoporosis/osteopenia in COPD patients in India.
Aim: To look for the degree and frequency of osteoporosis/osteopenia in our OPD patients being diagnosed as COPD.
Materials and methods: Thirty-seven randomly selected patients with COPD were assessed for BMD with commercially available ultrasound bone densitometer (HOLOGIC SAHARA) in a pulmonary OPD. Some cofactors for reduced BMD were also noted.
Results: Out of the 37 COPD (all belonging to the GOLD III/IV category) patients studied, the BMD was found to be normal in 10 (27%) patients, while 27 (73%) patients were found to have osteopenia/osteoporosis [19 (51.35%) and 8 (21.62%) patients having osteopenia and osteoporosis, respectively].
Conclusion: Frequency of osteoporosis and osteopenia was found to be very high (73%) in our population of advanced COPD. The data suggest a need for further in-depth study regarding the issue.
Keywords: Bone mineral density; chronic obstructive pulmonary disease; osteopenia; osteoporosis.
Conflict of interest statement
References
-
- Ionescu AA, Schoon E. Osteoporosis in chronic obstructive pulmonary disease. Eur Respir J. 2003;22(Suppl 46):64s–75. - PubMed
-
- Jorgensen NR, Schwartz P. Osteoporosis in chronic obstructive pulmonary disease patients. Curr Opin Pulm Med. 2008;14:122–7. - PubMed
-
- Mc Evoy CE, Ensrud KE, Bender E, Genant HK, Griffith JM, Niewoehner DE. Association between corticosteroid use and vertebral fractures in older men with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1998;157:704–9. - PubMed
-
- Calverly PM. The GOLD classification has advanced understanding of COPD. Am J Respir Crit Care Med. 2004;170:211–2. - PubMed
-
- Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: Report of a WHO study group. Geneva: 1994. World Health Organization. - PubMed
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