Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2009 Jul;13(2):89-92.
doi: 10.4103/0973-029X.57677.

Gorlin-Goltz syndrome

Deepti Singh Jawa  1 , Keya Sircar, Rani Somani, Neeraj Grover, Shipra Jaidka, Sanjeet Singh
Affiliations
Case Reports

Gorlin-Goltz syndrome

Deepti Singh Jawa et al. J Oral Maxillofac Pathol. 2009 Jul.

Abstract

Gorlin-Goltz syndrome is an autosomal dominant inherited disorder characterized by the presence of multiple odontogenic keratocysts along with various cutaneous, dental, osseous, ophthalmic, neurological, and sex organ abnormalities. Early diagnosis is essential as it may progress to aggressive basal cell carcinomas and neoplasias. Gorlin-Goltz syndrome has rarely been reported from India. We report here one such patient, diagnosed at a rural hospital.

Keywords: Diagnosis; Gorlin-Goltz syndrome; odontogenic keratocyst.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Sebaceous cyst over middle finger of the left hand
Figure 2
Figure 2
Sebaceous cyst on the back
Figure 3
Figure 3
Accessory toe with syndactily with 5th digit of right foot
Figure 4
Figure 4
Orthopantogram showing bilateral cyst with unerupted teeth
Figure 5
Figure 5
Chest X-ray showing bifid rib
Figure 6
Figure 6
Biopsy from right mandibular lesion showing odontogenic keratocyst showing characteristic cystic epithelial lining (H and E, ×10)
See this image and copyright information in PMC

References

    1. Stoelinga PJ, Peter JH, Van de Staak WJ, Cohen MM., Jr Some new findings in the basal cell nevus syndrome. Oral Surg. 1973;36:686–92. - PubMed
    1. Totten JR. The multiple nevoid basal cell carcinoma syndrome.Report of its occurrence in four generations of a family. Cancer. 1980;46:1456–62. - PubMed
    1. Walter AW. Gorlin Syndrome. Available from: http://www.emedicine.com/PED/topic890.htm .
    1. McDonald Ralph E, Avery Dean. Dentistry for the child and adolescent. 8th ed. Mosby; 2004. pp. 13–5.
    1. Gorlin RJ, Goltz RW. Multiple nevoid basal-cell epithelioma, jaw cysts and bifid rib. A syndrome. N Engl J Med. 1960;262:908–12. - PubMed

Publication types