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. 2011 Jun;49(6):329-33.
doi: 10.3340/jkns.2011.49.6.329. Epub 2011 Jun 30.

Surgical results of unruptured intracranial aneurysms in the elderly : single center experience in the past ten years

Young Jin Jung  1 , Jae Sung Ahn, Eun Suk Park, Do Hoon Kwon, Byung Duk Kwun, Chang Jin Kim
Affiliations

Surgical results of unruptured intracranial aneurysms in the elderly : single center experience in the past ten years

Young Jin Jung et al. J Korean Neurosurg Soc. 2011 Jun.

Abstract

Objective: As medical advances have increased life expectancy, it has become imperative to develop specific treatment strategies for intracranial aneurysms in the elderly. We therefore analyzed the clinical characteristics and outcomes of the treatment of unruptured intracranial aneurysms in patients older than 70 years.

Methods: We retrospectively reviewed the medical records and results of neuroimaging modalities on 54 aneurysms of 48 consecutive patients with unruptured intracranial aneurysms. (mean±SD age, 72.11±1.96 years; range, 70-78 years) who underwent surgical clipping over 10 years (May 1999 to June 2010).

Results: Of the 54 aneurysms, 22 were located in the internal carotid artery, 19 in the middle cerebral artery, 12 in the anterior cerebral artery, and 1 in the superior cerebellar artery. Six patients had multiple aneurysms. Aneurysm size ranged from 3 mm to 17 mm (mean±SD, 6.82±3.07 mm). Fifty of the 54 aneurysms (92.6%) were completely clipped. Three-month outcomes were excellent in 50 (92.6%) aneurysms and good and poor in 2 each (3.7%), with 1 death (2.0%). Procedure-related complications occurred in 7 aneurysms (13.0%), with 2 (3.7%) resulting in permanent neurological deficits, including death. No postoperative subarachnoid hemorrhage occurred during follow-up. The cumulative rates of stroke- or death-free survival at 5 and 10 years were 100% and 78%, respectively.

Conclusion: Surgical clipping of unruptured intracranial aneurysms in elderly group could get it as a favorable outcome in well selected cases.

Keywords: Elderly; Outcome; Surgical clipping; Unruptured intracranial aneurysm.

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Figures

Fig. 1
Fig. 1
Kaplan-Meier analysis of cumulative stroke- and death-free survival rate : 100% at 5 years and 77.8% at 10 years. The mean event-free survival was 159.44 months (95% confidence interval, 128.11-190.78 months).
Fig. 2
Fig. 2
A 72-year-old woman admitted to our institution due to headache and left eye ptosis. A : Preoperative computed tomography (CT) showing calcification in both basal ganglia but no definite high-density area in the basal or sylvian cistern. B : Transfemoral cerebral angiography showing a wide-necked large aneurysm on the left posterior communicating artery. C : Postoperative CT scan showing a high-density area in the left cerebellum. D : The patient died due to aggravated pneumonia and sepsis.
See this image and copyright information in PMC

References

    1. International Study of Unruptured Intracranial Aneurysms Investigators. Unruptured intracranial aneurysms--risk of rupture and risks of surgical intervention. N Engl J Med. 1998;339:1725–1733. - PubMed
    1. Ahn JS, Kwon Y, Kwun BD. Surgical management of unruptured intracranial aneurysms. J Korean Neurosurg Soc. 2000;29:330–335.
    1. Barker FG, 2nd, Amin-Hanjani S, Butler WE, Hoh BL, Rabinov JD, Pryor JC, et al. Age-dependent differences in short-term outcome after surgical or endovascular treatment of unruptured intracranial aneurysms in the United States, 1996-2000. Neurosurgery. 2004;54:18–28. discussion 28-30. - PubMed
    1. Cai Y, Spelle L, Wang H, Piotin M, Mounayer C, Vanzin JR, et al. Endovascular treatment of intracranial aneurysms in the elderly : single-center experience in 63 consecutive patients. Neurosurgery. 2005;57:1096–1102. discussion 1096-1102. - PubMed
    1. Chang HS. Simulation of the natural history of cerebral aneurysms based on data from the International Study of Unruptured Intracranial Aneurysms. J Neurosurg. 2006;104:188–194. - PubMed