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. 1990;12(1):37-42.
doi: 10.1111/j.1365-2257.1990.tb01108.x.

The use of D-Dimer assay by enzyme immunoassay and latex agglutination techniques in the diagnosis of deep vein thrombosis

C S Chapman  1 , N Akhtar, S Campbell, K Miles, J O'Connor, V E Mitchell
Affiliations

The use of D-Dimer assay by enzyme immunoassay and latex agglutination techniques in the diagnosis of deep vein thrombosis

C S Chapman et al. Clin Lab Haematol. 1990.

Abstract

The blood of 107 patients undergoing venography for suspected deep vein thrombosis (DVT) was tested for D-Dimers using enzyme immunoassay (EIA) and two latex agglutination techniques. D-Dimer levels by EIA were raised in 88% of patients with proven DVT. However, levels detected with the two agglutination tests were much less sensitive, being raised in only 43% patients with DVT. A more sensitive rapid screening test is needed to provide a useful non-invasive test for the exclusion of DVT.

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