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. 2011 Sep 2:3:22.
doi: 10.1186/1758-5996-3-22.

Low triglyceride levels are associated with a better metabolic control in patients with type 1 diabetes

Leticia M Alcantara #  1 , Nathalia E Silveira #  1 , Joana R Dantas  1 , Paula B Araujo  1 , Marcus M de Oliveira  1 , Adolpho Milech  1 , Lenita Zajdenverg  1 , Melanie Rodacki  1 , José Ep de Oliveira  1
Affiliations

Low triglyceride levels are associated with a better metabolic control in patients with type 1 diabetes

Leticia M Alcantara et al. Diabetol Metab Syndr. .

Abstract

Background: Although it is well known in the literature that high triglyceride serum (TG) levels can jeopardize the metabolic control, little is known about the influence of low TG on type 1 diabetes patients (T1D). The aim of this study is to investigate the distribution of TG serum levels in individuals with T1D and its relationship with metabolic control.

Findings: We reviewed the medical charts of 180 patients with T1D, who were classified in groups according to TG levels: 1) low (below 50 mg/dL); 2) normal (50-150 mg/dL); 3) high (above 150 mg/dL). TG were low in 21.1% (n = 38; group 1), normal in 68.6% (n = 123; group 2) and high in 10.6% (n = 19; group 3). High TG was associated with a poor metabolic control (p < 0.001). Patients with TG lower than 50 mg/dL had a lower HbA1c than those with TG between 50 and 150 mg/dL (7.41+/-1.50% vs 8.56%+/-1.94%; p = 0.002).

Conclusion: TG lower than 50 mg/dL was common and might be associated with a better metabolic control in patients with T1D, although it is not clear whether the former is the cause or consequence for the latter.

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Figures

Figure 1
Figure 1
HbA1c according to the groups with low, normal and high triglyceride. TGL: triglyceride level.
See this image and copyright information in PMC

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