Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011 Sep;40(3):473-84, vii.
doi: 10.1016/j.ecl.2011.05.009. Epub 2011 Jun 29.

Estrogen carcinogenesis in breast cancer

Doris Germain  1
Affiliations
Review

Estrogen carcinogenesis in breast cancer

Doris Germain. Endocrinol Metab Clin North Am. 2011 Sep.

Abstract

Many studies have reported a correlation between elevated estrogen blood levels and breast cancer and this observation has raised controversy concerning the long-term use of hormonal replacement therapy. This review will not address further this controversial topic; but rather, this review focuses on the role of estrogen signaling in first, the normal development of the breast and second, how alterations of this signaling pathway contribute to breast cancer.

PubMed Disclaimer

MeSH terms