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Clinical Trial
. 2011 Oct;53(7):693-5.
doi: 10.1093/cid/cir496.

High-dose oral fluconazole therapy effective for cutaneous leishmaniasis due to Leishmania (Vianna) braziliensis

Anastácio Q Sousa  1 , Mércia S Frutuoso, Elisabete A Moraes, Richard D Pearson, Margarida M L Pompeu
Affiliations
Clinical Trial

High-dose oral fluconazole therapy effective for cutaneous leishmaniasis due to Leishmania (Vianna) braziliensis

Anastácio Q Sousa et al. Clin Infect Dis. 2011 Oct.

Abstract

We report for the first time the successful use of fluconazole to treat cutaneous leishmaniasis due to Leishmania braziliensis. We used escalating doses from 5 to 8 mg/kg per day. At a dose of 5 mg/kg per day, 75% patients were cured, and at 8 mg/kg per day, the cure rate was 100%. Fluconazole was well tolerated.

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