Thorough work-up and new diagnostic criteria needed for CJD
- PMID: 21892213
- PMCID: PMC4134013
- DOI: 10.1038/nrneurol.2011.118
Thorough work-up and new diagnostic criteria needed for CJD
Abstract
The diagnosis of rapidly progressive dementias (RPDs), particularly sporadic Creutzfeldt–Jakob disease (sCJD), can prove challenging. Treatable RPDs might mimic sCJD, which is currently untreatable. A recent review of a large cohort of patients with suspected CJD highlights the extent of misdiagnosis and possible sources of error.
Conflict of interest statement
M. D. Geschwind declares associations with the following companies: The Council of Advisors for the Gerson–Lehman Group, Lundbeck, MedaCorp. See the article online for full details of the relationships. D. C. Perry declares no competing interests.
Comment on
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Treatable neurological disorders misdiagnosed as Creutzfeldt-Jakob disease.Ann Neurol. 2011 Sep;70(3):437-44. doi: 10.1002/ana.22454. Epub 2011 Jun 14. Ann Neurol. 2011. PMID: 21674591 Free PMC article.
References
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- Poser S, et al. How to improve the clinical diagnosis of Creutzfeldt–Jakob disease. Brain. 1999;122:2345–2351. - PubMed
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- World Health Organization. Global surveillance, diagnosis and therapy of human transmissible spongiform encephalopathies: Report of a WHO consultation. World Health Organization; 1998. [online] http://whqlibdoc.who.int/hq/1998/WHO_EMC_ZDI_98.9.pdf.
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