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. 2008:2:445-50.
doi: 10.4137/cmo.s366. Epub 2008 Jun 11.

B-cell lymphoma of the mandible: a case report

Ali Adouani  1 , Jed Bouguila, Yassine Jeblaoui, Mehdi Ben Aicha, Mouhamed Ali Abdelali, Mouna Hellali, Karima Zitouni, Landolsi Amani, Zairi Issam
Affiliations

B-cell lymphoma of the mandible: a case report

Ali Adouani et al. Clin Med Oncol. 2008.

Abstract

Introduction: The mandible is an infrequent localisation of primary osseous non-Hodgkin's lymphomas. Few cases of mandibular non-Hodgkin's lymphomas (NHL) have been reported.

Case report: A rare condition of primary malignant non-Hodgkin's lymphoma of the mandible in 53-year-old man, was reported at the Department of Maxillofacial and Plastic Surgery in Charles Nicolle Hospital (Tunis, Tunisia). Histologic and Immunohistochemical (IHC) examination Confirmed a B-Cell lymphoma.

Discussion: The purpose of this report is to describe this rare case of NHL of the mandible, explore the diagnosis and workup, and discuss treatment strategies. In this localisation, neither the clinical features nor the radiologic appearances are often pathognomonic.

Conclusion: Particular care must be taken to consider lymphoma in the differential diagnosis because this uncommon lesion can pose significant diagnostic problems and is frequently misdiagnosed.

Keywords: B-cell lymphoma; intraosseous lymphoma; mandible; non-Hodgkin’s lymphoma.

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Figures

Figure 1
Figure 1
Panoramic radiograph showing a diffuse radiolucent lesion in lower left molar region.
Figure 2
Figure 2
Computed tomagraphy showing a wide osteolytic area in the left part of the mandible.
Figure 3
Figure 3
Computed tomography showing a wide osteolytic area in the left part of the mandible.
Figure 4
Figure 4
Photomicrograph of the lymphoma showing bony trabeculae infiltrated by lmphoid population with a diffuse growth pattern (H-E).
Figure 5
Figure 5
Photomicrograph of immunohistochemical stain shows sheets of large mononuclear cells positive for CD20.
See this image and copyright information in PMC

References

    1. Angiero F, Stefani M, Crippa R. Primary non-Hodgkin’s lymphoma of the mandibular gingiva with maxillary gingival recurrence. Oral Oncology EXTRA. 2006;42:123–8.
    1. Bachaud JM, Coppin D, Douchez J, et al. Les lymphomes malins primitifs de la mandibule. Etude de 3 cas et revue de la litterature. Rev Stomatol Chir Maxillofac. 1992;93:372–6. - PubMed
    1. Steinbacher DM, Dolan RW. Isolated non-Hodgkin’s lymphoma of the mandible. Oral Oncology EXTRA. 2006;42:187–9.
    1. Ugar DA, Turker M, Memis L. Primary Lymphoma of the Mandible: Report of a Case. J Oral Maxillofac Surg. 1995;53:827–9. - PubMed
    1. Gusenbauer AW, Katsikeris NF, Brown A. Primary lymphoma of the mandible: report of a case. J Oral Maxillofac Surg. 1990;48:409–15. - PubMed

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