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Case Reports
. 2008:2:529-31.
doi: 10.4137/cmo.s693. Epub 2008 Aug 24.

Adenocarcinoma Arising within a Colonic Diverticulum in a Patient with Recurrent Diverticulitis

A van Beurden  1 , C I M Baeten, C P E Lange, H Doornewaard, L N L Tseng
Affiliations
Case Reports

Adenocarcinoma Arising within a Colonic Diverticulum in a Patient with Recurrent Diverticulitis

A van Beurden et al. Clin Med Oncol. 2008.

Abstract

In 2006, while admitted in our hospital for surgical treatment of recurrent diverticulitis, a 54-year-old man was found to have an adenocarcinoma arising within a colonic diverticulum. Computed tomography, during this episode of diverticulitis, showed a thickened wall of the sigmoid and inflammatory induration of the pericolonic fat. Colonoscopy could be performed up to no more then 25 cm from the anus due to mucosal edema. A sigmoid resection was performed. Histopathological examination of the resected specimen showed an inflamed diverticulum with a submucosal adenocarcinoma of the intestinal type within its wall. The surrounding flat colonic mucosa was not involved by the cancerous process. Due to lymph node involvement the patient received adjuvant chemotherapy and remained disease free during follow up.

Keywords: adenocarcinoma; colon; diverticulum.

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Figures

Figure 1
Figure 1
This picture shows a macroscopic view of a colon diverticulum. The fatty subserosal tissue contains some fibrous strands, which microscopically showed adenocarcinoma (arrow).
Figure 2
Figure 2
Microscopic examination of the resected specimen: a submucosal adenocarcinoma of the intestinal type, moderately differentiated, within the wall of a diverticulum A) In this section (HE-stained) the tumor cell cloths are marked by an arrow. B) A serial section shows Cytokeratin 20 positive staining (marker for adenocarcinoma).
See this image and copyright information in PMC

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