Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis
- PMID: 21892513
- DOI: 10.1039/c1cc14724b
Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis
Abstract
Herein, we describe a practical, one-pot variant of the sulfo-click reaction, in which 9-fluorenylmethyl-protected thioesters are rapidly deprotected and reacted further with sulfonylazides to give N-acyl sulfonamides.
This journal is © The Royal Society of Chemistry 2012
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