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. 2011 Oct 12;366(1579):2733-42.
doi: 10.1098/rstb.2011.0076.

Vaccines and global health

Brian Greenwood  1 , David Salisbury, Adrian V S Hill
Affiliations

Vaccines and global health

Brian Greenwood et al. Philos Trans R Soc Lond B Biol Sci. .

Abstract

Vaccines have made a major contribution to global health in recent decades but they could do much more. In November 2011, a Royal Society discussion meeting, 'New vaccines for global health', was held in London to discuss the past contribution of vaccines to global health and to consider what more could be expected in the future. Papers presented at the meeting reviewed recent successes in the deployment of vaccines against major infections of childhood and the challenges faced in developing vaccines against some of the world's remaining major infectious diseases such as human immunodeficiency virus (HIV), malaria and tuberculosis. The important contribution that development of more effective veterinary vaccines could make to global health was also addressed. Some of the social and financial challenges to the development and deployment of new vaccines were reviewed. The latter issues were also discussed at a subsequent satellite meeting, 'Accelerating vaccine development', held at the Kavli Royal Society International Centre. Delegates at this meeting considered challenges to the more rapid development and deployment of both human and veterinary vaccines and how these might be addressed. Papers based on presentations at the discussion meeting and a summary of the main conclusions of the satellite meeting are included in this issue of Philosophical Transactions of the Royal Society B.

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Figures

Figure 1.
Figure 1.
The vaccine development pathway.
See this image and copyright information in PMC

References

    1. Black R. E., et al. 2010. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet 375, 1969–1987 10.1016/S0140-6736(10)60549-1 (doi:10.1016/S0140-6736(10)60549-1) - DOI - PubMed
    1. Thompson D., Muriel P., Russell D., Osborne P., Bromley A., Rowland M., Creigh-Tyte S., Brown C. 2002. Economic costs of the foot and mouth disease outbreak in the United Kingdom in 2001. Rev. Sci. Technol. 21, 675–687 - PubMed
    1. Lu Y. J., et al. 2010. Options for inactivation, adjuvant, and route of topical administration of a killed, unencapsulated pneumococcal whole-cell vaccine. Clin. Vaccine Immunol. 17, 1005–1012 10.1128/CVI.00036-10 (doi:10.1128/CVI.00036-10) - DOI - PMC - PubMed
    1. Hoffman S. L., et al. 2010. Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria. Hum. Vaccines 6, 97–106 10.4161/hv.6.1.10396 (doi:10.4161/hv.6.1.10396) - DOI - PubMed
    1. Liu M. A. 2011. DNA vaccines: an historical perspective and view to the future. Immunol. Rev. 239, 62–84 10.1111/j.1600-065X.2010.00980.x (doi:10.1111/j.1600-065X.2010.00980.x) - DOI - PubMed

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