Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Apr;17(4):263-7.
doi: 10.1111/j.1440-1681.1990.tb01318.x.

Mechanisms involved in the stimulation of aldosterone production by angiotensin II, vasopressin and endothelin

E A Woodcock  1 , J K Tanner, L M Caroccia, P J Little
Affiliations

Mechanisms involved in the stimulation of aldosterone production by angiotensin II, vasopressin and endothelin

E A Woodcock et al. Clin Exp Pharmacol Physiol. 1990 Apr.

Abstract

1. Endothelin (ET), vasopressin (VP) and angiotensin II (AII) all stimulate aldosterone production in adrenal glomerulosa cells but the response to AII is greater than that to either ET or VP. 2. Total inositol phosphate responses to AII and ET were similar but the response to VP was lower. 3. Cytosolic free Ca2+ responses to AII were higher than to either of the other peptides. 4. Metabolism of 145IP3 was different under stimulation by the three different peptides. 5. Adrenal glomerulosa cells can distinguish between three different agonists which stimulate phosphatidylinositol turnover and produce a selective response to each peptide.

PubMed Disclaimer

Publication types

LinkOut - more resources