Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Sep;6(9):2121-31.
doi: 10.2215/CJN.11341210.

Cardiovascular disease among hispanics and non-hispanics in the chronic renal insufficiency cohort (CRIC) study

Ana C Ricardo  1 , James P Lash, Michael J Fischer, Claudia M Lora, Matthew Budoff, Martin G Keane, John W Kusek, Monica Martinez, Lisa Nessel, Thomas Stamos, Akinlolu Ojo, Mahboob Rahman, Elsayed Z Soliman, Wei Yang, Harold I Feldman, Alan S Go; CRIC and HCRIC Investigators
Collaborators, Affiliations

Cardiovascular disease among hispanics and non-hispanics in the chronic renal insufficiency cohort (CRIC) study

Ana C Ricardo et al. Clin J Am Soc Nephrol. 2011 Sep.

Abstract

Background and objectives: Hispanics are the largest minority group in the United States. The leading cause of death in patients with chronic kidney disease (CKD) is cardiovascular disease (CVD), yet little is known about its prevalence among Hispanics with CKD.

Design, setting, participants, & measurements: We conducted cross-sectional analyses of prevalent self-reported clinical and subclinical measures of CVD among 497 Hispanics, 1638 non-Hispanic Caucasians, and 1650 non-Hispanic African Americans, aged 21 to 74 years, with mild-to-moderate CKD at enrollment in the Chronic Renal Insufficiency Cohort (CRIC) and Hispanic CRIC (HCRIC) studies. Measures of subclinical CVD included left ventricular hypertrophy (LVH), coronary artery calcification (CAC), and ankle-brachial index.

Results: Self-reported coronary heart disease (CHD) was lower in Hispanics compared with non-Hispanic Caucasians (18% versus 23%, P = 0.02). Compared with non-Hispanic Caucasians, Hispanics had a lower prevalence of CAC >100 (41% versus 34%, P = 0.03) and CAC >400 (26% versus 19%, P = 0.02). However, after adjusting for sociodemographic factors, these differences were no longer significant. In adjusted analyses, Hispanics had a higher odds of LVH compared with non-Hispanic Caucasians (odds ratio 1.97, 95% confidence interval, 1.22 to 3.17, P = 0.005), and a higher odds of CAC >400 compared with non-Hispanic African Americans (odds ratio, 2.49, 95% confidence interval, 1.11 to 5.58, P = 0.03). Hispanic ethnicity was not independently associated with any other CVD measures.

Conclusions: Prevalent LVH was more common among Hispanics than non-Hispanic Caucasians, and elevated CAC score was more common among Hispanics than non-Hispanic African Americans. Understanding reasons for these racial/ethnic differences and their association with long-term clinical outcomes is needed.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Prevalence of coronary artery calcium scores (0, 1 to 100, >100 to 400, >400) by race/ethnicity among participants with eGFR <30ml/min/1.73m2 (1a) and diabetes (1b). NH, non-Hispanic.
See this image and copyright information in PMC

References

    1. US Census Bureau Hispanic Heritage Month 2010: Sept 15-Oct 15. US Census Bureau Newsroom Web site. http://www.census.gov/newsroom/releases/archives/facts_for_features_spec... Accessed March 1, 2011
    1. U.S. Renal Data System, USRDS 2010 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda MD, 2010
    1. Weiner DE, Tighiouart H, Amin MG, Stark PC, MacLeod B, Griffith JL, Salem DN, Levey AS, Sarnak MJ: Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: A pooled analysis of community-based studies. J Am Soc Nephrol 15: 1307–1315, 2004 - PubMed
    1. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351: 1296–1305, 2004 - PubMed
    1. Culleton BF, Larson MG, Wilson PW, Evans JC, Parfrey PS, Levy D: Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency. Kidney Int 56: 2214–2219, 1999 - PubMed

Publication types

Grants and funding