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. 2011 Jul;28(3):111-3.
doi: 10.4103/0970-9371.83467.

The clinical effectiveness of fine needle aspiration biopsy in patients with palpable breast lesions seen at the University College Hospital, Ibadan, Nigeria: A 10-year retrospective study

Cornelius O Ukah  1 , Olayiwola A Oluwasola
Affiliations

The clinical effectiveness of fine needle aspiration biopsy in patients with palpable breast lesions seen at the University College Hospital, Ibadan, Nigeria: A 10-year retrospective study

Cornelius O Ukah et al. J Cytol. 2011 Jul.

Abstract

Background: Although open surgical biopsy is the 'gold standard' for diagnosis of palpable breast lesions, in recent years two types of minimally invasive breast biopsy techniques, core needle biopsy and fine needle aspiration biopsy (FNAB), have become established for the diagnostic evaluation of palpable breast lesions.

Aims: This study was undertaken to evaluate the clinical effectiveness of FNAB as a first line diagnostic procedure in the management of patients with breast lumps in University College Hospital (UCH), Ibadan, using the suggested thresholds for cytology performance as recommended by the United Kingdom National Health Services Breast Screening Programme (NHSBSP).

Settings and design: A 10-year retrospective cohort study carried out in the Pathology Department of UCH.

Materials and methods: All FNAB and histologically diagnosed cases of breast lesions in the pathology department between January 1996 and December 2005 were reviewed. The cytological diagnoses were then categorized into one of five diagnostic categories in accordance with the recommendations of the NHSBSP.

Results: The positive predictive value for malignancy was 99.3% with a complete sensitivity of 97.7% and specificity (full) of 94.2%.

Conclusions: The high quality assurance measures obtained in this study affirms FNAB as a clinically effective diagnostic procedure for breast lesions.

Keywords: Clinical effectiveness; Nigeria; fine needle aspiration biopsy; palpable breast lesions.

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Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Litherland JC, Evans AJ, Wilson AR, Kollias J, Pinder SE, Elston CW, et al. The impact of core-biopsy on pre-operative diagnostic rate of screen detected breast cancers. Clin Radiol. 1996;51:562–5. - PubMed
    1. Ariga R, Bloom K, Reddy VB, Kluskens L, Francescatti D, Dowlat K, et al. Fine-needle aspiration of clinically suspicious palpable breast masses with histopathologic correlation. Am J Surg. 2002;184:410–3. - PubMed
    1. Robin L, Diana B, Liz A, Tom A, Ruth A, Tony R. Cytology subgroup of the national co-coordinating committee for breast screening pathology. Sheffield: NHS Cancer Screening Programme; 2001. Guidelines for cytology procedures and reporting in breast cancer screening.
    1. Kline TS, Joshi LP, Neal HS. Fine needle aspiration of the breast: Diagnosis and pitfalls. A review of 3545 cases. Cancer. 1979;44:1458–64. - PubMed
    1. Mohammed AZ, Edino ST, Ochicha O, Alhassan SU. Value of fine needle aspiration biopsy in preoperative diagnosis of palpable breast lumps in resource- poor countries: A Nigerian experience. Ann Afr Med. 2005;4:19–22.