doi: 10.1007/s00249-011-0746-8.
Epub 2011 Sep 6.
A model for dynamics of primer extension by eukaryotic DNA primase
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- PMID: 21898172
- DOI: 10.1007/s00249-011-0746-8
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A model for dynamics of primer extension by eukaryotic DNA primase
Eur Biophys J.
2011 Oct.
Abstract
A mathematical model is proposed for processive primer extension by eukaryotic DNA primase. The model uses available experimental data to predict rate constants for the dynamic behavior of primase activity as a function of NTP concentration. The model also predicts some data such as the binding affinities of the primase for the DNA template and for the RNA primer.
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