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Case Reports
. 2012 May;16(3):301-3.
doi: 10.1016/j.ejpn.2011.08.002. Epub 2011 Sep 7.

Rituximab in a childhood-onset idiopathic refractory chronic inflammatory demyelinating polyneuropathy

Adele D'Amico  1 , Michela Catteruccia, Fabrizio De Benedetti, Marina Vivarelli, Manuela Colucci, Simona Cascioli, Enrico Bertini
Affiliations
Case Reports

Rituximab in a childhood-onset idiopathic refractory chronic inflammatory demyelinating polyneuropathy

Adele D'Amico et al. Eur J Paediatr Neurol. 2012 May.

Abstract

Childhood-onset chronic inflammatory demyelinating polyneuropathy (CIDP) are generally responsive to conventional immunosuppressant treatments. However about 20% of patients may be refractory to several treatments and the disease has poor outcome. Rituximab is becoming a promising treatment in selected adult cases of severe CIDPs. We report the effectiveness of Rituximab in a refractory childhood-onset CIDP and we suggest this treatment as an effective choice in unresponsive childhood CIDP.

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