Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Feb;34(2):E19-21.
doi: 10.3174/ajnr.A2666. Epub 2011 Sep 8.

Creation of bifurcation-type elastase-induced aneurysms in rabbits

Y H Ding  1 , R Kadirvel, D Dai, D F Kallmes
Affiliations

Creation of bifurcation-type elastase-induced aneurysms in rabbits

Y H Ding et al. AJNR Am J Neuroradiol. 2013 Feb.

Abstract

Elastase incubation was performed in the LCCA in 13 New Zealand white rabbits. Three weeks after incubation, DSA demonstrated that 10 (10/13, 77%) bifurcation-type aneurysms at the origin of the LCCA were present; mean aneurysm neck, width, and height values were 3.7 ± 1.1, 3.8 ± 0.9, and 8.7 ± 2.3 mm, respectively. The LCCA can be used to create bifurcation aneurysms in rabbits.

PubMed Disclaimer

Figures

Fig 1.
Fig 1.
A−C, Anteroposterior IVDSA images show 3 bifurcation aneurysms (block arrow). D and E, 3D DSA images show 2 aneurysms located in the bifurcation between the aortic arch and brachiocephalic trunk (black arrow).
Fig 2.
Fig 2.
Anteroposterior (IVDSA) image shows a sidewall aneurysm originating from brachiocephalic trunk only (block arrow).
Fig 3.
Fig 3.
Anteroposterior IADSA image shows another sidewall aneurysm originating from aortic arch (block arrow).
See this image and copyright information in PMC

References

    1. Altes TA, Cloft HJ, Short JG, et al. 1999 ARRS Executive Council Award: creation of saccular aneurysms in the rabbit—a model suitable for testing endovascular devices. American Roentgen Ray Society. AJR Am J Roentgenol 2000;174:349–54 - PubMed
    1. Krings T, Hans FJ, Moller-Hartmann W, et al. Time-of-flight, phase contrast and contrast enhanced magnetic resonance angiography for pre-interventional determination of aneurysm size, configuration, and neck morphology in an aneurysm model in rabbits. Neurosci Lett 2002;326:46–50 - PubMed
    1. Ding YH, Dai D, Layton KF, et al. Vascular anatomic variation in rabbits. J Vasc Interv Radiol 2006;17:1031–35 - PubMed
    1. Ding YH, Dai D, Lewis DA, et al. Angiographic and histologic analysis of experimental aneurysms embolized with platinum coils, Matrix, and HydroCoil. AJNR Am J Neuroradiol 2005;26:1757–63 - PMC - PubMed
    1. Kallmes DF, Ding YH, Dai D, et al. A new endoluminal, flow-disrupting device for treatment of saccular aneurysms. Stroke 2007;38:2346–52 - PubMed

Publication types

MeSH terms