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. 2011:4:129-35.
doi: 10.2147/IDR.S10332. Epub 2011 Jul 21.

Treatment of drug-resistant tuberculosis

Affiliations

Treatment of drug-resistant tuberculosis

Lancelot Pinto et al. Infect Drug Resist. 2011.

Abstract

Clinical question: What is the best approach to the treatment of drug-resistant tuberculosis (TB)?

Results: Evidence-based treatment of drug-susceptible TB is the best means of preventing the development of drug-resistant disease. Suspecting the possibility of drug-resistant TB, and prompt detection of all forms of drug-resistant TB, not only multidrug-resistant and extensively drug-resistant TB, should be part of the algorithm for diagnosis and management of all patients with active TB.

Implementation: Treatment of all forms of drug-resistant TB must be tailored to the specific form of resistance with appropriate and effective drug regimens.

Keywords: MDR-TB; drug-resistant tuberculosis; treatment.

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References

    1. Treatment of tuberculosis: guidelines – 4th ed. WHO/HTM/TB/2009.420.
    1. World Health Organization . Anti-tuberculosis drug resistance in the world report no. 4. WHO/HTM/TB/2008.394.
    1. Mak A, Thomas A, Del Granado M, Zaleskis R, Mouzafarova N, Menzies D. Influence of multidrug resistance on tuberculosis treatment outcomes with standardized regimens. Am J Respir Crit Care Med. 2008;178(3):306–312. - PubMed
    1. Gandhi NR, Moll A, Sturm AW, et al. Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. Lancet. 2006;368(9547):1575–1580. - PubMed
    1. Mitnick CD, Shin SS, Seung KJ, et al. Comprehensive treatment of extensively drug-resistant tuberculosis. N Engl J Med. 2008;359(6):563–574. - PMC - PubMed

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