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Comment
. 2011 Sep 13;20(3):285-6.
doi: 10.1016/j.ccr.2011.08.018.

Tissue states provide novel insights into attributes that drive metastasis

Thea D Tlsty  1
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Tissue states provide novel insights into attributes that drive metastasis

Thea D Tlsty. Cancer Cell. .
Free article

Abstract

Recently, in Nature Medicine, Schedin and colleagues define attributes within the involuting postpartum breast microenvironment that promote breast cancer metastasis. Cell invasiveness is controlled by a positive feedback loop involving COX-2 and fibrillar collagen. NSAIDs suppress tumor progression during postpartum involution, potentially providing effective agents for intervention in pregnant women.

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