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Clinical Trial
. 1990 May;31(5):514-7.
doi: 10.1136/gut.31.5.514.

Abolition by omeprazole of aspirin induced gastric mucosal injury in man

T K Daneshmend  1 , A G Stein, N K Bhaskar, C J Hawkey
Affiliations
Clinical Trial

Abolition by omeprazole of aspirin induced gastric mucosal injury in man

T K Daneshmend et al. Gut. 1990 May.

Abstract

This study investigates whether aspirin injury to the human gastric mucosa can be prevented by profound acid suppression with omeprazole, in a randomised, double blind, crossover design according to latin square. It was concluded that profound acid suppression can prevent aspirin induced gastric mucosal injury in normal subjects. This approach may prevent the development of peptic ulcers and their complications in patients taking aspirin and other non-steroidal anti-inflammatory drugs.

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References

    1. Gut. 1982 Apr;23(4):340-4 - PubMed
    1. Dig Dis Sci. 1979 Jul;24(7):525-8 - PubMed
    1. Eur J Pharmacol. 1983 Jul 15;91(1):111-4 - PubMed
    1. Digestion. 1983;27(3):159-64 - PubMed
    1. Br J Clin Pharmacol. 1984 Oct;18(4):587-90 - PubMed

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