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. 2011 Apr;31(2):145-167.
doi: 10.1097/TLD.0b013e318217b855.

A multigenerational family study of oral and hand motor sequencing ability provides evidence for a familial speech sound disorder subtype

Beate Peter  1 , Wendy H Raskind
Affiliations

A multigenerational family study of oral and hand motor sequencing ability provides evidence for a familial speech sound disorder subtype

Beate Peter et al. Top Lang Disord. 2011 Apr.

Abstract

PURPOSE: To evaluate phenotypic expressions of speech sound disorder (SSD) in multigenerational families with evidence of familial forms of SSD. METHOD: Members of five multigenerational families (N = 36) produced rapid sequences of monosyllables and disyllables and tapped computer keys with repetitive and alternating movements. RESULTS: Measures of repetitive and alternating motor speed were correlated within and between the two motor systems. Repetitive and alternating motor speeds increased in children and decreased in adults as a function of age. In two families with children who had severe speech deficits consistent with disrupted praxis, slowed alternating, but not repetitive, oral movements characterized most of the affected children and adults with a history of SSD, and slowed alternating hand movements were seen in some of the biologically related participants as well. CONCLUSION: Results are consistent with a familial motor-based SSD subtype with incomplete penetrance, motivating new clinical questions about motor-based intervention not only in the oral but also the limb system.

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Figures

Figure 1
Figure 1
Durations (ms) from the monosyllable repetition task (/pα/) and the repetitive key tapping task as a function of age in months.
Figure 2
Figure 2
Durations (ms) from the disyllable repetition task (/pαta/) and the alternating key tapping task as a function of age in months.
Figure 3
Figure 3
Ratios of repetitive/alternating key tapping (KT) durations as a function of age in months. Labels are participant codes for adults with ratios <1.
Figure 4
Figure 4
Ratios of monosyllable and disyllable durations as a function of age in months. Labels are participant codes for adults with ratios <1.
Figure 5
Figure 5
/pα, pαta/ z-score differences as a function of age in months. Labels are participant codes for differences > 1.
See this image and copyright information in PMC

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