Light-induced cytotoxicity of a photochromic spiropyran
- PMID: 21909522
- DOI: 10.1039/c1cc13561a
Light-induced cytotoxicity of a photochromic spiropyran
Abstract
In this work we present a novel water soluble spiropyran photoswitch that can be photonically activated inside live cells from a form that has no significant effect on the cellular survival to a form that induces a dramatic toxic response.
Similar articles
-
Molecular AND-logic for dually controlled activation of a DNA-binding spiropyran.Chem Commun (Camb). 2010 Oct 14;46(38):7130-2. doi: 10.1039/c0cc01682a. Epub 2010 Aug 27. Chem Commun (Camb). 2010. PMID: 20820507
-
Photoswitched DNA-binding of a photochromic spiropyran.J Am Chem Soc. 2008 Sep 10;130(36):11836-7. doi: 10.1021/ja801968f. Epub 2008 Aug 13. J Am Chem Soc. 2008. PMID: 18698779
-
Alkylation of spiropyran moiety provides reversible photo-control over nanostructured soft materials.Biointerphases. 2012 Dec;7(1-4):3. doi: 10.1007/s13758-011-0003-9. Epub 2012 Feb 9. Biointerphases. 2012. PMID: 22589046
-
Novel photochromic inhibitor for mitotic kinesin Eg5 which forms multiple isomerization states.J Biochem. 2021 Oct 11;170(2):229-237. doi: 10.1093/jb/mvab035. J Biochem. 2021. PMID: 33752234
-
Phase-Separated Spiropyran Coacervates as Dual-Wavelength-Switchable Reactive Oxygen Generators.Angew Chem Int Ed Engl. 2025 Feb 17;64(8):e202419538. doi: 10.1002/anie.202419538. Epub 2025 Jan 22. Angew Chem Int Ed Engl. 2025. PMID: 39746885 Free PMC article.
Cited by
-
Synthesis, Photochromic and Luminescent Properties of Ammonium Salts of Spiropyrans.Molecules. 2022 Dec 2;27(23):8492. doi: 10.3390/molecules27238492. Molecules. 2022. PMID: 36500585 Free PMC article.
-
New Triphenylphosphonium Salts of Spiropyrans: Synthesis and Photochromic Properties.Molecules. 2024 Jan 11;29(2):368. doi: 10.3390/molecules29020368. Molecules. 2024. PMID: 38257281 Free PMC article.
-
Molecular photoswitches in aqueous environments.Chem Soc Rev. 2021 Nov 15;50(22):12377-12449. doi: 10.1039/d0cs00547a. Chem Soc Rev. 2021. PMID: 34590636 Free PMC article. Review.
-
Spiropyran/Merocyanine Amphiphile in Various Solvents: A Joint Experimental-Theoretical Approach to Photophysical Properties and Self-Assembly.Int J Mol Sci. 2022 Sep 29;23(19):11535. doi: 10.3390/ijms231911535. Int J Mol Sci. 2022. PMID: 36232836 Free PMC article.
-
Photochromic and Luminescent Properties of a Salt of a Hybrid Molecule Based on C60 Fullerene and Spiropyran-A Promising Approach to the Creation of Anticancer Drugs.Molecules. 2023 Jan 22;28(3):1107. doi: 10.3390/molecules28031107. Molecules. 2023. PMID: 36770772 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources