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Review
. 2011 Sep 6;4(190):tr3.
doi: 10.1126/scisignal.2001967.

Introduction to statistical methods to analyze large data sets: principal components analysis

Neil R Clark  1 , Avi Ma'ayan
Affiliations
Review

Introduction to statistical methods to analyze large data sets: principal components analysis

Neil R Clark et al. Sci Signal. .

Abstract

This Teaching Resource provides lecture notes, slides, and a problem set for a series of lectures from a course entitled "Systems Biology: Biomedical Modeling." The materials are a lecture introducing the mathematical concepts behind principal components analysis (PCA). The lecture describes how to handle large data sets with correlation methods and unsupervised clustering with this popular method of analysis, PCA.

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References

    1. Médez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma’ayan A, Enikolopov GN, Frenette PS. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 2010;466:829–834. - PMC - PubMed

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