Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009:2009:bcr11.2008.1193.
doi: 10.1136/bcr.11.2008.1193. Epub 2009 Sep 15.

Progressive respiratory distress due to neck mass

Affiliations

Progressive respiratory distress due to neck mass

Raquel F D van la Parra et al. BMJ Case Rep. 2009.

Abstract

The present report describes the case of an 80-year-old woman who presented at the emergency department with progressive respiratory distress caused by a massive anterior neck mass with tracheal deviation and compression. A CT scan showed diffuse enlargement of the thyroid gland. The patient underwent a left-sided hemithyroidectomy. Pathology unexpectedly revealed a primary thyroid lymphoma. Treatment with prednisone and vincristine was initiated to reduce tumour size and preserve the airway, resulting in rapid volume reduction and airway expansion. Primary thyroid lymphoma is a rare entity that requires adequate diagnosis and rapid initiation of treatment to reduce tumour volume and to prevent airway compromise.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Macroscopy. Left-sided hemithyroidectomy mass.
Figure 2
Figure 2
Preoperative CT image. Thyroid mass with tracheal compression.
Figure 3
Figure 3
Postoperative CT image. Post left-sided hemithyroidectomy. Tracheal compression resolved.
Figure 4
Figure 4
Pathology slide. A. Low power magnification (2.5×) of the thyroid surrounded by partly necrotic lymphoid tissue. B. The higher magnification (40×) shows large atypical lymphoid cells, which were positive for CD20 (not shown).

References

    1. Kalinyak JE, Kong CS, McDougall IR. Burkitt’s lymphoma presenting as a rapidly growing thyroid mass. Thyroid 2006; 16: 1053–7 - PubMed
    1. Harish K, Murali S, Kilara N, et al. Cutaneous ulceration in thyroid lymphoma. Thyroid 2008; 18: 909–10 - PubMed
    1. Van den BA, Drijkoningen M, Oyen R, et al. Diagnostic fine-needle aspiration cytology and immunocytochemistry analysis of a primary thyroid lymphoma presenting as an anatomic emergency. Thyroid 2002; 12: 169–73 - PubMed
    1. Yang H, Li J, Shen T. Primary T-cell lymphoma of the thyroid: case report and review of the literature. Med Oncol 2008; 25: 462–6 - PubMed

LinkOut - more resources