Signatures for drug repositioning

Comment

Charlotte Harrison. Nat Rev Genet. 2011.

. 2011 Sep 16;12(10):668.

doi: 10.1038/nrg3076.

No abstract available

Comment on

Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease.
Dudley JT, Sirota M, Shenoy M, Pai RK, Roedder S, Chiang AP, Morgan AA, Sarwal MM, Pasricha PJ, Butte AJ. Dudley JT, et al. Sci Transl Med. 2011 Aug 17;3(96):96ra76. doi: 10.1126/scitranslmed.3002648. Sci Transl Med. 2011. PMID: 21849664 Free PMC article.
Discovery and preclinical validation of drug indications using compendia of public gene expression data.
Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Sage J, Butte AJ. Sirota M, et al. Sci Transl Med. 2011 Aug 17;3(96):96ra77. doi: 10.1126/scitranslmed.3001318. Sci Transl Med. 2011. PMID: 21849665 Free PMC article.