doi: 10.1128/mcb.10.7.3852-3856.1990.
Transfected human beta-polymerase promoter contains a ras-responsive element
Affiliations
- PMID: 2192267
- PMCID: PMC360856
- DOI: 10.1128/mcb.10.7.3852-3856.1990
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Transfected human beta-polymerase promoter contains a ras-responsive element
Mol Cell Biol.
1990 Jul.
Abstract
beta-Polymerase is a vertebrate cellular DNA polymerase involved in gap-filling synthesis during some types of genomic DNA repair. We report that a cloned human beta-polymerase promoter in a transient expression assay is activated by p21v-rasH expression in NIH 3T3 cells. A decanucleotide palindromic element, GTGACGTCAC, at positions -49 to -40 in the promoter is required for this ras-mediated stimulation.
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