Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Jul;10(7):3852-6.
doi: 10.1128/mcb.10.7.3852-3856.1990.

Transfected human beta-polymerase promoter contains a ras-responsive element

P S Kedar  1 , D R Lowy, S G Widen, S H Wilson
Affiliations

Transfected human beta-polymerase promoter contains a ras-responsive element

P S Kedar et al. Mol Cell Biol. 1990 Jul.

Abstract

beta-Polymerase is a vertebrate cellular DNA polymerase involved in gap-filling synthesis during some types of genomic DNA repair. We report that a cloned human beta-polymerase promoter in a transient expression assay is activated by p21v-rasH expression in NIH 3T3 cells. A decanucleotide palindromic element, GTGACGTCAC, at positions -49 to -40 in the promoter is required for this ras-mediated stimulation.

PubMed Disclaimer

References

    1. Virology. 1973 Apr;52(2):456-67 - PubMed
    1. Nucleic Acids Res. 1990 Feb 25;18(4):919-28 - PubMed
    1. J Virol. 1980 Jul;35(1):76-92 - PubMed
    1. Proc Natl Acad Sci U S A. 1982 Jun;79(11):3637-40 - PubMed
    1. Mol Cell Biol. 1982 Sep;2(9):1044-51 - PubMed

Substances

LinkOut - more resources