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. 1990 Jun 15;169(2):451-4.
doi: 10.1016/0006-291x(90)90352-n.

The effect of amylin and calcitonin gene-related peptide on insulin-stimulated glucose transport in the diaphragm

J S Hothersall  1 , R P Muirhead, S Wimalawansa
Affiliations

The effect of amylin and calcitonin gene-related peptide on insulin-stimulated glucose transport in the diaphragm

J S Hothersall et al. Biochem Biophys Res Commun. .

Abstract

The two peptides calcitonin gene related peptide (CGRP) and amylin at 1 uM levels in an isolated rat diaphragm preparation inhibited insulin stimulated 2-deoxy[3H]glucose transport by 30 and 60 percent, respectively; this was the case at maximal (1 uM) and sub-maximal (0.5 mU) insulin concentrations. No effect was measured on the basal level of 2-deoxy[3H]glucose transport.

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