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. 1990 May;17(5):455-7.
doi: 10.1007/BF00334527.

Interactions between the yeast mitochondrial and nuclear genomes: isogenic suppressive and hypersuppressive petites differ in their resistance to the alkaloid lycorine

D R Massardo  1 , F Manna, L Del Giudice, K Wolf
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Interactions between the yeast mitochondrial and nuclear genomes: isogenic suppressive and hypersuppressive petites differ in their resistance to the alkaloid lycorine

D R Massardo et al. Curr Genet. 1990 May.

Abstract

In a previous paper we have shown that the alkaloid lycorine inhibits growth of rho+, mit- and rho-, strains of Saccharomyces cerevisiae, whereas strains devoid of mitochondrial DNA (rho degrees) are resistant to more than 200 micrograms/ml of the alkaloid. In this report we show that hypersuppressive petites are almost as resistant as rho degrees mutants, whereas isogenic rho- petites, which have retained longer segments of the genome, are sensitive to the drug.

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References

    1. Proc Natl Acad Sci U S A. 1980 Jul;77(7):3942-6 - PubMed
    1. Mol Cell Biol. 1989 May;9(5):1897-907 - PubMed
    1. Curr Genet. 1984 Sep;8(7):493-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1972 Jun;69(6):1371-4 - PubMed
    1. Philos Trans R Soc Lond B Biol Sci. 1988 May 31;319(1193):127-33 - PubMed

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