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. 2009:2009:bcr03.2009.1677.
doi: 10.1136/bcr.03.2009.1677. Epub 2009 Sep 20.

Precocious puberty and a sellar mass

Anil Bhansali  1 , P Jayaprakash, Pinaki Dutta, Rama Walia, P Ravikumar
Affiliations

Precocious puberty and a sellar mass

Anil Bhansali et al. BMJ Case Rep. 2009.

Abstract

Precocious puberty in a child less than 3 years of age is usually gonadotropin dependent and is often associated with extrasellar central nervous system disorders. The present report describes the case of a 2½-year-old girl who presented with gonadotropin-independent precocious puberty and had a sellar mass. She was referred for neurosurgical intervention to our institute. On investigation, she was found to have primary hypothyroidism of autoimmune aetiology, which is rarely associated with precocious puberty and sellar mass due to thyrotroph hyperplasia. She was successfully treated with levothyroxine, and with this secondary sexual characteristics progressively regressed and the sellar mass disappeared.

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Figures

Figure 1
Figure 1
A. Bilateral breast enlargement (B4, Tanner scale). B. T1-weighted MRI showing isointense pituitary mass with suprasellar extension (arrow) measuring 17.3×12.5×11.9 mm.
Figure 2
Figure 2
A. Complete regression of the breast enlargement after 3 months of levothyroxine treatment. B. T1-weighted MRI showing complete regression of the pituitary mass (arrow).
See this image and copyright information in PMC

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