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Case Reports
. 2011 Nov;38(11):1066-1071.
doi: 10.1111/j.1346-8138.2011.01254.x. Epub 2011 Sep 20.

Case of primary localized cutaneous amyloidosis with protean clinical manifestations: lichen, poikiloderma-like, dyschromic and bullous variants

Nisha Suyien Chandran  1 , Boon-Kee Goh  1 , Siong-See Lee  1 , Chee-Leok Goh  1
Affiliations
Case Reports

Case of primary localized cutaneous amyloidosis with protean clinical manifestations: lichen, poikiloderma-like, dyschromic and bullous variants

Nisha Suyien Chandran et al. J Dermatol. 2011 Nov.

Abstract

Primary localized cutaneous amyloidosis (PLCA) commonly presents as macular and lichen variants. We present a case of a 27-year-old Chinese woman with cutaneous features of the rarely reported poikiloderma-like, dyschromic and bullous forms of PLCA, and the commoner lichen variant. There were no syndromic associations or systemic involvement, and the various morphological subtypes occurred in isolation from one another. We review the clinical spectrum of PLCA, highlight its protean clinical manifestations in this patient, and discuss its postulated pathogenesis in relation to its histopathological features.

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