Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011 Sep 20;12(10):929-30.
doi: 10.1038/ni.2118.

STING-dependent signaling

Glen N Barber
Comment

STING-dependent signaling

Glen N Barber. Nat Immunol. .

Erratum in

  • Nat Immunol. 2012 Feb;13(2):196

Abstract

The sensing of pathogen-associated DNA in the cytoplasm is an important trigger of host-defense responses that include the production of type I interferon. A new study suggests that the DExDc helicase DDX41 may function in dendritic cells as a DNA sensor to activate STING-dependent innate immune responses.

PubMed Disclaimer

Comment on

References

    1. Nat Immunol. 2010 Nov;11(11):997-1004 - PubMed
    1. Cell. 2010 Mar 19;140(6):821-32 - PubMed
    1. Nature. 2007 Jul 26;448(7152):501-5 - PubMed
    1. Nat Immunol. 2011 Sep 04;12(10):959-65 - PubMed
    1. Nature. 2009 Oct 8;461(7265):788-92 - PubMed

LinkOut - more resources