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Comparative Study
. 2011 Oct;27(5):325-9.
doi: 10.1007/s12264-011-1531-5.

Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

Paulo Roberto Correia  1 , Fulvio Alexandre Scorza, Sérgio Gomes da Silva, Aline Pansani, Michelle Toscano-Silva, Antonio Carlos de Almeida, Ricardo Mario Arida
Affiliations
Comparative Study

Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

Paulo Roberto Correia et al. Neurosci Bull. 2011 Oct.

Abstract
in English, Chinese

Objective: Exercise is known to enhance circulating brain-derived neurotrophic factor (BDNF) levels in healthy humans. BDNF changes have been measured in endurance but not in strength exercise. The present study aimed to investigate whether anaerobic activity such as sprinting differentially alters basal plasma BDNF concentration.

Methods: Brazilian sprinters (100 m) at either the international (Olympics and Outdoor World Championships) (n = 14) or the domestic level (n = 8), and sedentary subjects (n = 15), were recruited. Plasma BDNF concentrations were analyzed by enzyme-linked immunosorbent assay.

Results: The basal plasma BDNF concentrations were significantly higher in the international and the domestic sprinters than in the sedentary subjects. In addition, sprinters at the international level had higher plasma BDNF concentrations than those at the domestic level.

Conclusion: Our findings suggest that increased basal plasma BDNF level is related to enhanced exercise performance.

目的: 目前研究发现锻炼能增强健康人血液中脑源性神经营养因子(BDNF)的水平。 BDNF水平的改变常发现于耐力运动而非力量锻炼。 本研究旨在探讨厌氧型活动(如短跑)是否能改变人血浆中BDNF的浓度。

方法: 对22名巴西100米短跑运动员, 包括14名过去4年间参加过国际级奥林匹克及户外世锦赛的运动员(国际级)和8名只参加过本国比赛的运动员(国内级), 以及15名此前从未参加过任何运动比赛的健康对照人群, 用ELISA法检测其血浆中BDNF的水平。

结果: 与对照组相比, 国际级和国内级短跑运动员血浆中BDNF的水平均显著升高。 此外, 国际级短跑运动员血浆中BDNF的水平显著高于国内级运动员。

结论: 血浆中BDNF水平的升高可能与运动加强有关。

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References

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