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Editorial
. 2011 Nov;20(11):1471-7.
doi: 10.1517/13543784.2011.619978. Epub 2011 Sep 21.

Insulin-like growth factor 1 receptor (IGF-1R) inhibitor: another arrow in the quiver - Will it hit the moving target?

Vivek Subbiah, Laura S Angelo, Razelle Kurzrock
Editorial

Insulin-like growth factor 1 receptor (IGF-1R) inhibitor: another arrow in the quiver - Will it hit the moving target?

Vivek Subbiah et al. Expert Opin Investig Drugs. 2011 Nov.

Abstract

Insulin-like growth factor 1 receptor (IGF-1R) inhibitors have anti-tumor activity in various cancers. The development of IGF-1R inhibitors is a multi-dimensional and complex issue, involving many different drugs, and affecting several different points along the pathway. Matching patients with these agents based on molecular profiling/signatures will be essential for the proper development of this type of targeted agent.

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