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Clinical Trial
. 1990 May-Jun;18(3):201-9.
doi: 10.1177/030006059001800304.

Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome

I Caruso  1 , P Sarzi Puttini, M Cazzola, V Azzolini
Affiliations
Clinical Trial

Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome

I Caruso et al. J Int Med Res. 1990 May-Jun.

Abstract

A double-blind, placebo-controlled study of the efficacy and tolerability of 5-hydroxytryptophan (5-HTP) was conducted in 50 patients with primary fibromyalgia syndrome. All the clinical parameters studied were significantly improved by treatment with 5-HTP and only mild and transient side-effects were reported. Further controlled studies are required to define properly the value of 5-HTP in patients with primary fibromyalgia syndrome.

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