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Review
. 2011 Oct;21(4):567-81.
doi: 10.1016/j.giec.2011.07.004. Epub 2011 Aug 10.

Epidemiology and demographics of upper gastrointestinal bleeding: prevalence, incidence, and mortality

Affiliations
Review

Epidemiology and demographics of upper gastrointestinal bleeding: prevalence, incidence, and mortality

Carlos Sostres et al. Gastrointest Endosc Clin N Am. 2011 Oct.

Abstract

Despite major advances in diagnosis, prevention, and treatment, nonvariceal upper gastrointestinal bleeding still is a serious problem in clinical practice. Current evidence indicates that most peptic ulcer bleeding-linked deaths are not a direct sequela of the bleeding ulcer itself. Instead, mortality derives from multiorgan failure, cardiopulmonary conditions, or terminal malignancy, suggesting that improving further current treatments for the bleeding ulcer may have a limited impact on mortality unless supportive therapies are developed for the global management of these patients.

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