Chemical activators of ClpP: turning Jekyll into Hyde

Affiliations

Comment

David A Dougan. Chem Biol. 2011.

. 2011 Sep 23;18(9):1072-4.

doi: 10.1016/j.chembiol.2011.09.003.

¹ Department of Biochemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne 3086, Australia. d.dougan@latrobe.edu.au

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Comment on

Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease.
Leung E, Datti A, Cossette M, Goodreid J, McCaw SE, Mah M, Nakhamchik A, Ogata K, El Bakkouri M, Cheng YQ, Wodak SJ, Eger BT, Pai EF, Liu J, Gray-Owen S, Batey RA, Houry WA. Leung E, et al. Chem Biol. 2011 Sep 23;18(9):1167-78. doi: 10.1016/j.chembiol.2011.07.023. Chem Biol. 2011. PMID: 21944755