In two parallel pragmatic equivalence trials, leukotriene receptor antagonists as initial therapy for asthma compared with inhaled corticosteroids and as add on therapy to ICS compared with adding long-acting β agonists provided equivalent short-term asthma quality of life but were associated with more medication switches
- PMID: 21949261
- DOI: 10.1136/ebm.2011.100140
In two parallel pragmatic equivalence trials, leukotriene receptor antagonists as initial therapy for asthma compared with inhaled corticosteroids and as add on therapy to ICS compared with adding long-acting β agonists provided equivalent short-term asthma quality of life but were associated with more medication switches
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Leukotriene antagonists as first-line or add-on asthma-controller therapy.N Engl J Med. 2011 May 5;364(18):1695-707. doi: 10.1056/NEJMoa1010846. N Engl J Med. 2011. PMID: 21542741 Clinical Trial.
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