Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Sep;16(9):095003.
doi: 10.1117/1.3622492.

Common-path low-coherence interferometry fiber-optic sensor guided microincision

Kang Zhang  1 , Jin U Kang
Affiliations

Common-path low-coherence interferometry fiber-optic sensor guided microincision

Kang Zhang et al. J Biomed Opt. 2011 Sep.

Abstract

We propose and demonstrate a common-path low-coherence interferometry (CP-LCI) fiber-optic sensor guided precise microincision. The method tracks the target surface and compensates the tool-to-surface relative motion with better than ± 5 μm resolution using a precision micromotor connected to the tool tip. A single-fiber distance probe integrated microdissector was used to perform an accurate 100 μm incision into the surface of an Intralipid phantom. The CP-LCI guided incision quality in terms of depth was evaluated afterwards using three-dimensional Fourier-domain optical coherence tomography imaging, which showed significant improvement of incision accuracy compared to free-hand-only operations.

PubMed Disclaimer

Figures

Figure 1
Figure 1
(a) Schematic for CP-LCI guided microincision. S, distance between fiber sensor tip and microdissector tip; d, distance from fiber sensor tip to target tissue surface; H, microincision depth. (b) Design of the free hand-holding tool, IN: inner needle for surgical tool mounting; ON: outer needle for protection and alignment; ST: surgical tip; PM: piezoelectric micromotor; MC: micromotor cord; SMF: single mode fiber. (c) A CP-LCI integrated microdissector made from a hypodermic needle. (d) A prototype of the handheld tool.
Figure 2
Figure 2
System schematic. CCD, CCD line scan camera; G, grating; L1, L2 achromatic lenses.
Figure 3
Figure 3
(a) System control flowchart; (b) speed control curve.
Figure 4
Figure 4
Results for motion compensation.
Figure 5
Figure 5
CP-LCI guided micro-incision: (a) En face projection image of the incision region; (b) B-scan along the red trace (right line) in (a), bottom of incision; (c) B-scan along the blue trace (left line) in (a), top of incision; (d) combination of (b) and (c). The free-hand micro-incision situation is performed as (e) and (f), corresponding to (a) and (b), respectively. The green arrows on (a) and (e) indicate the incision direction. (Color online only.)
See this image and copyright information in PMC

References

    1. Riviere C. N., Ang W. T., and Khosla P. K., “Toward active tremor canceling in handheld microsurgical instruments,” IEEE Trans. Rob. Autom. 19, 793–800 (2003).10.1109/TRA.2003.817506 - DOI
    1. Hsu P. A. and Cooley B. C., “Effect of exercise on microsurgical hand tremor,” Microsurgery 23, 323–327 (2003).10.1002/micr.10156 - DOI - PubMed
    1. Rizzo S., Patelli F., and Chow D. R., Vitreo-retinal Surgery, Springer-Verlag, Berlin Heidelberg: (2009).
    1. Latt W. T., Tan U. X., Shee C. Y., Riviere C. N., and Ang W. T., “Compact sensing design of a handheld active tremor compensation instrument,” IEEE Sens. J. 9, 1864–1871 (2009).10.1109/JSEN.2009.2030980 - DOI - PMC - PubMed
    1. Zhang K., Wang W., Han J. H., and Kang J. U., “A surface topology and motion compensation system for microsurgery guidance and intervention based on common-path optical coherence tomography,” IEEE Trans. Biomed. Eng. 56, 2318–2321 (2009).10.1109/TBME.2009.2024077 - DOI - PMC - PubMed

Publication types