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Comparative Study
. 2012 Feb;74(2):231-4.
doi: 10.1292/jvms.10-0565. Epub 2011 Sep 28.

Comparison of behavioral effects of morphine and fentanyl in dogs and cats

Masatoshi Kamata  1 , Shotaro Nagahama, Kei Kakishima, Nobuo Sasaki, Ryohei Nishimura
Affiliations
Free article
Comparative Study

Comparison of behavioral effects of morphine and fentanyl in dogs and cats

Masatoshi Kamata et al. J Vet Med Sci. 2012 Feb.
Free article

Abstract

Behavioral effects induced by intravenous administration of morphine at 0.3, 0.6, 1.2, and 2.4 µg/kg and fentanyl at 5, 10, 20, and 40 µg/kg were evaluated in dogs and cats. In dogs, fentanyl and morphine depressed activity and level of consciousness in a dose- dependant manner. In cats, higher doses of fentanyl stimulated activity temporarily, but excitement, so-called "opioid mania," was not observed. Morphine induced distinctive behavioral changes characterized by sitting with fixed staring, and "opioid mania" was not observed in cats.

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