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Case Reports
. 2011 Apr;2(2):106-9.
doi: 10.4103/0976-237X.83073.

Neoplastic potential of odontogenic cysts

Zama Moosvi  1 , S Amsavardani Tayaar, G S Kumar
Affiliations
Case Reports

Neoplastic potential of odontogenic cysts

Zama Moosvi et al. Contemp Clin Dent. 2011 Apr.

Abstract

Odontogenic cysts and tumors are distinct entities and quite a common occurrence in the jaw bones. The lining of odontogenic cysts shows a potential for neoplastic transformation to non odontogenic malignancies like squamous cell carcinoma and mucoepidermoid carcinoma, and odontogenic tumors like ameloblastoma and adenoamatoid odontogenic tumor (AOT). AOT is a benign, epithelial odontogenic tumor, common site being the anterior maxilla. Its origin from a dentigerous cyst and in the mandible is rare. A case of an AOT arising from a dentigerous cyst associated with an impacted permanent mandibular left lateral incisor is reported.

Keywords: Adenoamtoid odontogenic tumor; dentigerous cyst; impacted mandibular lateral incisor; neoplastic transformation; pathogenesis.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Paranasal sinus (PNS) X-ray view showing welldefined radiolucency in the parasymphysis region associated with unerupted 32
Figure 2
Figure 2
Photomicrograph showing thin stratified squamous non keratinized epithelial lining of dentigerous cyst with a fibrous connective tissue wall and few inflammatory cells (H and E, ×100)
Figure 3
Figure 3
Cut section of the gross specimen, showing proliferations from the periphery of the mass into the lumen and mass attached to the neck of the tooth
Figure 4a
Figure 4a
Scanner view showing cyst lining gradually transforming to whorls of elongated cuboidal cells and connective tissue stroma arranged circumferential to the lumen with few chronic inflammatory cells. (H and E, ×40)
Figure 4b
Figure 4b
Photomicrograph showing lining of ntigerous cyst and loose connective tissue wall with few inflammatory cells. (H and E, ×250)
Figure 4c
Figure 4c
Photomicrograph showing cyst lining gradually transforming to elongated cuboidal cells of AOT and connective tissue wall with few inflammatory cells. (H and E, ×250)
Figure 5
Figure 5
Photomicrograph showing cells arranged in whorls and duct like patterns with calcification. (H and E, ×250)
Figure 6
Figure 6
Photomicrograph showing cords, whorls and few duct like patterns of round to ovoid cells in a scanty fibrillar connective tissue stroma. (H and E, ×100)
See this image and copyright information in PMC

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