Focal nodular hyperplasia--a review of myths and truths

Abstract

Background: Focal nodular hyperplasia (FNH) is a benign hyperplastic lesion of the liver with no known malignant potential. It has generated much interest due to the frequency with which it presents with atypical features on radiological imaging. Often resulting in misdiagnosis. Moreover, the understanding of particular subtypes of this lesion at a molecular level has changed in recent years. This may have implications on how certain subtypes should be managed.

Purpose: This review aims to analyse current literature pertaining to FNH and to provide clinically relevant advice regarding diagnosis and management.