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. 2012 Mar;119(3):381-2.
doi: 10.1007/s00702-011-0716-4. Epub 2011 Sep 30.

Heterogenous mechanisms of mild cognitive impairment in Parkinson's disease

Kurt Jellinger  1
Affiliations

Heterogenous mechanisms of mild cognitive impairment in Parkinson's disease

Kurt Jellinger. J Neural Transm (Vienna). 2012 Mar.

Abstract

Mild cognitive impairment in Parkinson disease (PD-MCI) shows heterogeneity in the clinical presentation, neuropsychology, neuroimaging, and neuropathology, suggesting abnormal metabolic network activities involving several cortical and subcortical systems. Prospective studies using specific biomarkers, including amyloid imaging and CSF biomarkers are important for the diagnosis and prognostic assessment of early cognitive deficits in PD patients.

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